NPAS2 Antibody

Cat no: 252085

Supplier: ABBIOTEC

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Description
Additional Information

Neuronal PAS domain-containing protein 2 (NPAS2) forms heterodimers which activate E-bo, Xenopus/Amphibian, element (3'-CACGTG-5') transcription of a number of proteins of the circadian clock. This transcription is inhibited in a feedback loop by PER, and also by CRY proteins. NPAS2 is a component of the circadian clock oscillator which includes the CRY proteins, CLOCK or NPAS2, BMAL1 or BMAL2, CSNK1D and/or CSNK1E, TIMELESS and the PER proteins. Efficient DNA binding requires dimerization with another bHLH protein. Heterodimerization with CLOCK or NPAS2 is required for E-bo, Xenopus/Amphibian,-dependent transactivation.

Catalogue number:	252085
Reactivities:	Human
Applications:	Western Blot
Size:	0.1 mg
Accession:	Q99743
Antigen:	KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human NPAS2.
Format:	Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.
P type:	Rabbit Polyclonal Antibody
Isotype:	Rabbit Ig
Additional info:	Neuronal PAS domain-containing protein 2; Neuronal PAS2; Member of PAS protein 4; Basic-heli, Xenopus/Amphibian,-loop-heli, Xenopus/Amphibian,-PAS protein MOP4; PAS domain-containing protein 4; Class E basic heli, Xenopus/Amphibian,-loop-heli, Xenopus/Amphibian, protein 9; bHLHe9; NPAS2; BHLHE9; MOP4; PASD4