NRas Antibody

Cat no: 251515

Supplier: ABBIOTEC

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Description
Additional Information

GTPase NRas (NRas) binds GDP/GTP and possess intrinsic GTPase activity. Alternate between an inactive form bound to GDP and an active form bound to GTP. Activated by a guanine nucleotide-e, Xenopus/Amphibian,change factor (GEF) and inactivated by a GTPase-activating protein (GAP). Defects in NRAS are a cause of juvenile myelomonocytic leukemia (JMML). JMML is a pediatric myelodysplastic syndrome that constitutes appro, Xenopus/Amphibian,imately 30% of childhood cases of myelodysplastic syndrome (MDS) and 2% of leukemia.

Catalogue number:	251515
Reactivities:	Human, Mouse, Rabbit
Applications:	Immunohistochemistry
Size:	0.1 mg
Accession:	P01111
Antigen:	KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human NRas.
Format:	Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.
P type:	Rabbit Polyclonal Antibody
Isotype:	Rabbit Ig
Additional info:	GTPase NRas; Transforming protein N-Ras; NRAS; HRAS1