NRF1 (TCF11, alpha pal, alpha palindromic binding protein, Alpha-pal, locus control region factor 1, NFE2 related factor 1, NRF-1, Nrf1, nuclear factor (erythroid derived 2)-like 1, nuclear respiratory factor 1, transcription factor 11)

This gene encodes a protein that homodimerizes and functions as a transcription factor which activates the expression of some key metabolic genes regulating cellular growth and nuclear genes required for respiration, heme biosynthesis, and mitochondrial DNA transcription and replication. The protein has also been associated with the regulation of neurite outgrowth. Alternate transcriptional splice variants, which encode the same protein, have been characterized. Additional variants encoding different protein isoforms have been described but they have not been fully characterized. Confusion has occurred in bibliographic databases due to the shared symbol of NRF1 for this gene and for ""nuclear factor (erythroid-derived 2)-like 1"" which has an official symbol of NFE2L1. [provided by RefSeq, Jul 2008]"\n\nApplications: \nSuitable for use in Western Blot. Other applications not tested. \n\nRecommended Dilution:\nWestern Blot: 1:1000\nOptimal dilutions to be determined by the researcher. \n\nStorage and Stability:\nMay be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

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SPECIFICATIONS

Catalog Number

143257

Size

100ul

Applications

WB

Hosts

Mouse

Reactivities

Hum

Form

Supplied as a liquid in PBS, pH 7.4, 0.1% BSA, 0.2% sodium azide, 50% glycerol.

P Type

Mab

Purity

Purified by immunoaffinity chromatography.

Isotype

IgG2a

Additional Info

Recognizes endogenous levels of NRF1. Does not cross-react with related proteins. Species Crossreactivity: human

Alternative Names

(alpha pal, alpha palindromic binding protein, Alpha-pal, locus control region factor 1, NFE2 related factor 1, NRF-1, Nrf1, nuclear factor (erythroid derived 2)-like 1, nuclear respiratory factor 1, transcription factor 11)