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NRG2, ID (Pro-neuregulin-2, membrane-bound isoform [Precursor], Pro-NRG2, NRG2, NTAK,)

Cat no: 039146

NRG2, ID (Pro-neuregulin-2, membrane-bound isoform [Precursor], Pro-NRG2, NRG2, NTAK,)

Neuregulin 2 (NRG2) is a novel member of the neuregulin family of growth and differentiation factors. Through interaction with the Erbb family of receptors, NRG2 induces the growth and differentiation of epithelial, neuronal, glial, and other types of cells. The gene consists of 12 exons and the genomic structure is similar to that of neuregulin 1 (NRG1), another member of the neuregulin family of ligands. NRG1 and NRG2 mediate distinct biological processes by acting at different sites in tissues and eliciting different biological responses in cells. There are six NRG2 alternatively spliced transcripts which are variable between the epidermal growth factor-like (EGF-like) and the transmembrane domains. The gene is located close to the region for demyelinating Charcot-Marie-Tooth disease locus, but is not responsible for this disease.\n\nApplications:\nSuitable for use in ELISA\n\nRecommended Dilution:\nELISA: 1:1,000\n\nStorage and Stability:\nMay be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

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SPECIFICATIONS

Catalog Number

039146

Size

200ul

Applications

ELISA

Hosts

Rabbit

Reactivities

Hum

Form

Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.

P Type

Pab

Purity

Purified by Protein G affinity chromatography.

Isotype

IgG

Additional Info

Human

Alternative Names

Pro-neuregulin-2, membrane-bound isoform [Precursor], Pro-NRG2, NRG2, NTAK,

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