NT5E (1D7) Antibody

Cat no: 252906

Supplier: ABBIOTEC

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Description
Additional Information

NT5E (CD73 (Cluster of Differentiation 73)) is an ecto-5'-nucleotidase. NT5E catalyzes the conversion at neutral pH of purine 5-prime mononucleotides to nucleosides, the preferred substrate being AMP. The enzyme consists of a dimer of 2 identical 70-kD subunits bound by a glycosyl phosphatidyl inositol linkage to the e, Xenopus/Amphibian,ternal face of the plasma membrane. The enzyme is used as a marker of lymphocyte differentiation. Consequently, a deficiency of NT5 occurs in a variety of immunodeficiency diseases. Other forms of 5-prime nucleotidase e, Xenopus/Amphibian,ist in the cytoplasm and lysosomes and can be distinguished from ecto-NT5 by their substrate affinities, requirement for divalent magnesium ion, activation by ATP, and inhibition by inorganic phosphate.

Catalogue number:	252906
Reactivities:	Human
Applications:	Immunohistochemistry
Size:	0.1 ml
Accession:	Q96B60
Antigen:	Purified recombinant fragment of NT5E e, Xenopus/Amphibian,pressed in E. coli.
Format:	Each vial contains 0.1 ml ascitic fluid with 0.03% sodium azide.
P type:	Mouse Monoclonal Antibody
Isotype:	Mouse IgG1
Clonality:	1D7
Additional info:	eN; NT5; CD73; 5'-nucleotidase, ecto (CD73)