Nuclear Pore Comple, Xenopus/Amphibian, Antibody

Cat no: 253196

Supplier: ABBIOTEC

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Description
Additional Information

The nuclear pore comple, Xenopus/Amphibian, (NPC) is a very large structure made up of at least 50 different proteins that span the double membrane of the nuclear envelope functioning as a gateway for macromolecular traffic between the cytoplasm and the nucleus. Discrete nuclear pore comple, Xenopus/Amphibian, proteins or nucleoporins such as NUP98, NUP180 and p62 have been implicated in autoimmune disease and cancer. Patients with primary biliary cirrhosis (PBC) frequently produce autoantibodies against p62 and NUP180 while NUP98 translocations have been found in patients with acute myelogenous leukemia (AML).

Catalogue number:	253196
Reactivities:	Human, Mouse, Rabbit
Applications:	Immunofluorescence
Size:	0.1 ml
Antigen:	Yeast nuclear preparations.
Format:	Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of HEPES (pH7.5), 0.01% BSA, 50% glycerol with 0.065% sodium azide. Antibody was purified by Protein-G affinity chromatography.
P type:	Mouse Monoclonal Antibody
Isotype:	Mouse IgG1
Clonality:	39C7
Additional info:	Yeast nuclear preparations.