Nurr1 Antibody

Cat no: 250795

Supplier: ABBIOTEC

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Description
Additional Information

Nuclear receptors and transcription factors play a role in the development and maintenance of neurons that synthesize the neurotransmitter dopamine. The NURR1 gene encodes a 67-kDa member of the steroid-thyroid hormone-retinoid receptor superfamily. The orphan nuclear receptor NURR1 may function as a general coactivator of gene transcription and transcription factor. Mutations in Nurr1 have been associated with disorders related to dopaminergic dysfunction, including Parkinson disease, schizophrenia, and maniac depression. Misregulation of Nurr1 may be associated with rheumatoid arthritis.

Catalogue number:	250795
Reactivities:	Human, Mouse, Rabbit
Applications:	Immunohistochemistry
Size:	0.1 mg
Accession:	P43354
Antigen:	KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human NURR1.
Format:	Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.
P type:	Rabbit Polyclonal Antibody
Isotype:	Rabbit Ig
Additional info:	Nuclear receptor subfamily 4 group A member 2; Orphan nuclear receptor NURR1; Immediate-early response protein NOT; Transcriptionally-inducible nuclear receptor; NR4A2; NOT; NURR1; TINUR