Nystatin is a mixture of the byproducts of Streptomyces noursei. Nystatin belongs to the group of medicines called antifungals. Nystatin works by binding to a substance called ergosterol, which is a component of fungal cell membranes. Binding to ergosterol disrupts the cell membrane and causes holes to appear.
Activity: (same/more than)5000U/mg
Loss on Drying: (same/less than)5%
pH (3%): 6.0-8.0
Suspendibility, Crystallinity, Identification and Composition: To pass test
Storage and Stability:
Lyophilized powder may be stored at -20 degrees C. Stable for 12 months at -20 degrees C. Reconstitute with sterile buffer. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
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