Octreotide, Human (Somatostatin analog)

Supplier:

United States Biological

Cat no: O5575-05

Octreotide, Human (Somatostatin analog)

Octreotide acetate is a longer acting synthetic octapeptide analog of naturally occurring somatostatin. It inhibits the secretion of gastro-entero-pancreatic peptide hormones and the release of growth hormone.\n\nSynthetic Human Octreotide is a single, non-glycosylated, polypeptide chain containing 8aa.\n\nAmino Acid Sequence: \nThe sequence was determined to be H-D-Phe-Cys-Phe-D-Trp-Lys-Thr-Cys-L-threoninol\n\nSolubility: \nIt is recommended to reconstitute the lyophilized Octreotide in sterile 18MOmega-cm H2O not less than 100ug/ml, which can then be further diluted to other aqueous solutions.\n\nStorage and Stability:\nLyophilized powder may be stored at 4 degrees C for short-term only. Reconstitute to nominal volume by adding sterile dH2O and store at -20 degrees C. Reconstituted product is stable for 12 months at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

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SPECIFICATIONS

Catalog Number

O5575-05

Size

1mg

Form

Supplied as a sterile-filtered, lyophilized powder with no additives.

Purity

Purified by proprietary chromatographic techniques. (same/more than) 98.0% as determined by: (a) RP-HPLC. (b) Anion-exchange FPLC. (c) Reducing and non-reducing SDS-PAGE Silver Stained gel.

References

1. Sclerotherapy plus octreotide versus sclerotherapy alone in the management of gastro-oesophageal variceal hemorrhage. J Ayub Med Coll Abbottabad 2005 Jan-Mar;17(1):10-4.\n2. Case 3. Oncogenic osteomalacia associated with hemangiopericytoma localized by octreotide scan. J Clin Oncol 2005 May 20;23(15):3626-8.\n3. Production of pro- and anti-fibrotic agents by rat Kupffer cells; the effect of octreotide. Dig Dis Sci 2005 May;50(5):935-41.\n4. Pituitary tumor disappearance in a patient with newly diagnosed acromegaly primarily treated with octreotide LAR. J Endocrinol Invest 2005 Feb;28(2):166-9.\n5. Octreotide in insulinoma patients: efficacy on hypoglycemia, relationships with Octreoscan scintigraph y and immunostaining with anti-sst2A and anti-sst5 antibodies. Eur J Endocrinol 2005 May;152(5):757-67.\n6. Characterization of 68Ga-DOTA-D-Phe1-Tyr3-octreotide kinetics in patients with meningiomas. J Nucl Med 2005 May;46(5):763-9.

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SUPPLIER INFO

United States Biological

Address:

4 Technology Way, Salem, MA 01970, US

Phone:

+1 800 520 3011

Website:

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