One Step Staining Mouse Treg Flow(TM) Kit (FOXP3 Alexa Fluor(R) 488/CD25 PE/CD4 PerCP)

Cat no: 136801

Supplier: BioLegend

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Description
Additional Information

T regulatory (Treg) cells are a subset of T lymphocytes which is characterized by CD4+/CD25+/FOXP3+. These naturally occurring Treg cells originate in the thymus, and comprise 2-10% of peripheral CD4+ T cells. It has been shown that Treg cells are able to inhibit T cells proliferation and cytokine production and play critical roles in preventing autoimmunity as well as in controlling tumor immunity and transplantation tolerance. Impaired Treg function or Treg cell deficiency will develop variety of autoimmune diseases, while higher frequency of Treg cells will cause hypo-immune response to pathogens. BioLegend's One Step Staining Mouse Treg Flow(TM) Kit is designed and formulated specifically for immunofluorescence staining and flow cytometric analysis of mouse Treg cells in a mixed lymphocyte population. This kit is composed of fluorochrome conjugated anti-mouse CD4, CD25 and FOXP3 antibodies and the critical buffers. It is an one-step staining kit for labeling both surface and intracellular antigens of Treg cells.

Catalogue number:	136801
Reactivities:	Mouse
Hosts:	Rat
Applications:	Flow Cytometry, Immunocytochemistry
Size:	25 tests
Clone:	MF-14
Gene:	20371
Storage buffer:	This kit is guaranteed for three months.
Isotype:	Rat IgG2b, kappa
Clonality:	Monoclonal
Regulatory status:	RUO
Shipping temp:	Ambient RT
Storage temp:	4 C
Alternative names:	Forkhead box protein P3, Scurfin, JM2, IPEX, Zinc finger protein JM2