ORM1 pAb

Alpha 1 acid glycoprotein (AGP) is an acute phase plasma protein synthesized by the liver. It functions to regulate the interaction between blood cells and endothelial cells, and together with haptoglobin and C reactive protein, it also mediates the extravasation of cells during infection and inflammation. Expression of AGP is induced by acute-phase stimulatory agents such as bacterial lipopolysaccharides. AGP has a high affinity, low capacity binding for basic drugs at physiological pH. In human plasma, AGP is found at 0.5-1.4 mg/ml. These levels are elevated during acute inflammation; therefore AGP protein levels can be used to diagnose inflammatory conditions. Multiple AGP genes exist, including AGP 1, AGP 2, AGP 3 and AGP 8. AGP 1 and AGP 2 contain five and six potential N-glycosylation sites, respectively. Abnormal expression of the APG 1 gene is linked to sarcoidosis and other immunogenetic diseases, while mutations in the APG 2 gene are associated with different types of carcinomas.

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SPECIFICATIONS

Catalog Number

BS6685

Size

100ug/100ul

Applications

IHC, WB

Hosts

Rabbit

Reactivities

Hum

Form

liquid

Purity

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Antigen

Recombinant full length Human ORM1.

Species

ORM1 pAb detects endogenous levels of ORM1 protein.

Dilutions

WB: 1:500~1:2000\nIHC: 1:50~1:200

Swiss Prot

P02763

Storage Temp

Store at 4 degrees C short term. Aliquot and store at -20 degrees C long term. Avoid freeze-thaw cycles.

Concentration

1ug/ul

Storage Buffer

1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.

Additional Info

For research use only, not for use in diagnostic procedure.

Molecular Weight

~ 24 kDa

Alternative Names

A1AG1; AGP 1; AGP A; AGP; agp1; agpa; Alpha 1 acid glycoprotein; Alpha 1 agp; Alpha-1-acid glycoprotein 1; Glycoprotein alpha acid of serum; OMD 1; omd1; orm; ORM1; Orosomucoid 1; Orosomucoid-1; Orosomucoid1;