OX40L, Soluble, Recombinant, Mouse (ACRP30headless:OX40L, ACRP30headless:CD252, ACRP30headless:CD134L)

Cat no: 045124

Supplier: United States Biological

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OX40L is a membrane-expressed cytokine that belongs to the TNF ligand family. It acts as costimulator through interaction with its ligand OX40 on T cells, stimulating T cell activation, proliferation and cytokine production. OX40L is expressed on antigen presenting cells including B cells, dendritic cells, mast cells and endothelium. MegaOX40L(TM) is a high activity construct in which two trimeric OX40L ligands are artificially linked via the collagen domain of ACRP30. This construct very effectively activates T cell proliferation. Biological Activity: Activates T cell proliferation. Sequence: The extracellular domain of mouse OX40L (aa 52-199) is fused at the N-terminus to mouse ACRP30headless (aa 18-111) and a FLAG(R)-tag. Storage and Stability: Short-term Storage: +4 degrees C Long-term Storage: -20 degrees C Stable for at least 6 months after receipt when stored at -20 degrees C.

Catalogue number:	045124
Size:	10ug
Form:	Supplied as a lyophilized powder from a 0.2um filtered solution in PBS pH 7.2.
Purity:	>90% (SDS-PAGE)
Alternative names:	ACRP30headless:OX40L, ACRP30headless:CD252, ACRP30headless:CD134L
References:	Product Reference: ?Endothelial cell co-stimulation through OX40 augments and prolongs T cell cytokine synthesis by stabilization of cytokine mRNA: J. Mestas, et al.; Int. Immun. 17, 737 (2005) ?
Additional info:	Binds to human and mouse OX40.

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OX40L, Soluble, Recombinant, Mouse (ACRP30headless:OX40L, ACRP30headless:CD252, ACRP30headless:CD134L)

Cat no: 045124

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