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p-Arrestin-beta-1 (S412) Peptide

p-Arrestin-beta-1 (S412) Peptide

Cat no: BS4292P

Supplier: Bioworld Technology, Inc.
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Beta Arrestin 1 is a member of a family of proteins that are widely expressed but especially abundant in the central nervous system. Serving as an adaptor or scaffold molecule, beta Arrestin 1 is essential for mitogenic signaling. Beta Arrestin 1 has important roles in the cytoplasm and at the plasma membrane in the desensitization and internalization of G protein coupled receptors (GPCRs) and is increasingly appreciated to play an important role in the endocytosis and signaling of GPCRs. Beta Arrestin 1 in the cytosol is phosphorylated by ERK1 and 2 on serine 412 in a negative feedback mechanism and binds to the phosphorylated receptors at the plasma membrane.
Catalogue number: BS4292P
Applications: Block/Neutralize/Inhibit
Swiss prot: P49407
Form: 1 mg/ml in DI water.
Purity: Synthetic peptide p-Arrestin-beta-1 (S412). (Note: the amino acid sequence is proprietary). The purity is > 98%.
Storage temp: Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.
Alternative names: ARB 1; ARB1; ARR 1; ARR1; ARRB 1; ARRB1; Arrestin 2; Arrestin beta 1; Arrestin beta-1; Beta-arrestin-1; Arrestin-beta1; Arrestin beta1; beta-arrestin-1
Additional info: This peptide can be used with studies using BS4292 p-Arrestin-beta-1 (S412) pAb.

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