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p-Bcl-2 (T69) Peptide

p-Bcl-2 (T69) Peptide

Cat no: BS4294P

Supplier: Bioworld Technology, Inc.
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Bcl-2 is one among many key regulators of apoptosis which are essential for proper development, tissue homeostasis and protection against foreign pathogens. Human Bcl-2 is a 26 kDa, membraneassociated, anti-apoptotic oncoprotein that can promote cell survival through protein-protein interactions with other Bcl-2 related family members, such as the death suppressors Bcl-xL, Mcl-1, Bcl-w and A1, or the death agonists Bax, Bak, Bik, Bad and BID. The anti-apoptotic function of Bcl-2 can also be regulated through proteolytic processing and phosphorylation. Bcl-2 may promote cell survival by interfering with the activation of the cytochrome c/Apaf-1 pathway through stabilization of the mitochondrial membrane.
Catalogue number: BS4294P
Applications: Block/Neutralize/Inhibit
Swiss prot: P10415
Form: 1 mg/ml in DI water.
Purity: Synthetic peptide p-Bcl-2 (T69). (Note: the amino acid sequence is proprietary). The purity is > 98%.
Storage temp: Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.
Alternative names: Apoptosis regulator Bcl-2; Bcl 2; BCL2
Additional info: This peptide can be used with studies using BS4294 p-Bcl-2 (T69) pAb.

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