p-C/EBP-beta (T235/188) Peptide

C/EBP beta is a member of the C/EBP transcription factor family. The C/EBP beta gene encodes several isoforms, which have truncated transcription activation domains by the alternative translational initiation at multipe AUG start sites. Initiation of translation at the in-frame AUGs forms four C/EBP beta isoforms. C/EBP beta is also known as interleukin 6-dependent DNA-binding protein (IL6DBP), liver activator protein(LAP) or liver-enriched transcriptional activator protein transcription factor 5 (TCF5). C/EBP beta contributes to the regulation of the acute phase response in hepatocytes. Stat3 has an important function in IL-6-mediated transcription of the C/EBP beta gene that has direct implication for acute phase response in liver cells.The 35 kDa C/EBP beta form requires phosphorylation for its DNA binding ability, and increased binding of C/EBP beta isoforms during acute-phase reaction occurs through its upregulation and structural modification.

Prices direct from Bioworld Technology, Inc.

Quick response times

Exclusive Biosave savings/discounts

SPECIFICATIONS

Catalog Number

BS4029P

Applications

BNI

Form

1 mg/ml in DI water.

Purity

Synthetic peptide p-C/EBP-beta (T235/188). (Note: the amino acid sequence is proprietary). The purity is > 98%.

Swiss Prot

P17676

Storage Temp

Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.

Additional Info

This peptide can be used with studies using BS4029 p-C/EBP-beta (T235/188) pAb.

Alternative Names

CCAAT/enhancer-binding protein beta; C/EBP beta; C/EBPbeta; C/EBP beta; Liver activator protein; LAP; Liver-enriched inhibitory protein; LIP; Nuclear factor NF-IL6; Transcription factor 5; TCF-5; CEBPB; TCF5; ORF Names: PP9092