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p-CD3 ? (Y142) Peptide

p-CD3 ? (Y142) Peptide

Cat no: BS4304P

Supplier: Bioworld Technology, Inc.
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Probable role in assembly and expression of the TCR complex as well as signal transduction upon antigen triggering. The TCR/CD3 complex of T-lymphocytes consists of either a TCR alpha/beta or TCR gamma/delta heterodimer coexpressed at the cell surface with the invariant subunits of CD3 labeled gamma, delta, epsilon, zeta, and eta. CD3-zeta forms either homodimers or heterodimers with CD3-eta. Interacts with SLA and SLA2. Interacts with DOCK2 and TRAT1. Interacts with HIV-1; this interaction up-regulates the expression of the Fas ligand (FASLG) at the cell surface. Interacts with HIV-2 Nef protein; this interaction induces down-regulation of cell surface TCR/CD3 complexes.
Catalogue number: BS4304P
Applications: Block/Neutralize/Inhibit
Swiss prot: P20963
Form: 1 mg/ml in DI water.
Purity: Synthetic peptide p-CD3 ? (Y142). (Note: the amino acid sequence is proprietary). The purity is > 98%.
Storage temp: Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.
Alternative names: T-cell surface glycoprotein CD3 zeta chain; T-cell receptor T3 zeta chain; CD247; CD247; CD3Z; T3Z; TCRZ; CD3?; CD3-?
Additional info: This peptide can be used with studies using BS4304 p-CD3 ? (Y142) pAb.

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