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p-eIF4B(Ser422) Peptide

p-eIF4B(Ser422) Peptide

Cat no: AP0084P

Supplier: Bioworld Technology, Inc.
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Required for the binding of mRNA to ribosomes. Functions in close association with EIF4-F and EIF4-A. Binds near the 5'-terminal cap of mRNA in presence of EIF-4F and ATP. Promotes the ATPase activity and the ATP-dependent RNA unwinding activity of both EIF4-A and EIF4-F.It is phosphorylated at Ser-422 by RPS6KA1 and RPS6KB1.phosphorylation enhances the affinity of EIF4B for the EIF3 complex
Catalogue number: AP0084P
Applications: Block/Neutralize/Inhibit
Swiss prot: P23588
Form: 1 mg/ml in DI water.
Purity: Synthetic peptide p-eIF4B(Ser422). (Note: the amino acid sequence is proprietary). The purity is > 98%.
Storage temp: Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.
Alternative names: EIF 4B; EIF-4B; Eukaryotic initiation factor 4B; Eukaryotic translation initiation factor 4B; PRO1843;
Additional info: This peptide can be used with studies using AP0084 p-eIF4B(Ser422) pAb.

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