p-Ephrin-B1/2 (Y330)

Ephrin-B proteins are transmembrane and have conserved cytoplasmic tyrosine residues that are phosphorylated upon interaction with an EphB receptor. Eph receptors and ephrins exhibit complementary expression in many tissues during embryogenesis indicating that bidirectional activation of Eph receptors and ephrin-B proteins may occur at expression domain interfaces. Ephrin-B1 transduces outside-in signals through C-terminal protein interactions that effect integrin-mediated cell attachment and migration. The distribution of ephrin-B1 in the developing retina suggests that it influences retinal axon mapping along the dorsal-ventral axis and may be involved in intratectal development The transmembrane ligand ephrin-B2 and its receptor tyrosine kinase EphB4 are specifically expressed on arterial and venous endothelial cells, respectively.

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SPECIFICATIONS

Catalog Number

BS4068P

Applications

BNI

Form

1 mg/ml in DI water.

Purity

Synthetic peptide p-Ephrin-B1/2 (Y330). (Note: the amino acid sequence is proprietary). The purity is > 98%.

Swiss Prot

P52799

Storage Temp

Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.

Additional Info

This peptide can be used with studies using BS4068 p-Ephrin-B1/2 (Y330).

Alternative Names

CEK5 ligand; EFNB1; ELK L; ELK ligand; ELKL; EPH related receptor tyrosine kinase ligand 2; Ephrin B Precursor; Ephrin B1; Ephrin B2; LERK 2; LERK2; Ephrin B