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p-OLIG2 (S147) Peptide

p-OLIG2 (S147) Peptide

Cat no: AP0734P


Supplier: Bioworld Technology, Inc.
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OLIG1 and OLIG2 are specifically expressed in nervous tissue as gene regulators of oligodendrogenesis. OLIG2 is more widely expressed in embryonic brain than OLIG1, while OLIG3 is primarily expressed in non-neural tissues. OLIG1 and OLIG2 interact with the Nkx-2.2 homeodomain protein, which is responsible for directing ventral neuronal patterning in response to graded Sonic hedgehog signaling in the embryonic neural tube. These interactions between OLIG proteins and Nkx-2.2 appear to promote the formation of alternate cell types by inhibiting V3 interneuron development. OLIG1 and OLIG2 are abundantly expressed in oligodendroglioma and nearly absent in astrocytomas.
Catalogue number: AP0734P
Applications: Block/Neutralize/Inhibit
Swiss prot: Q13516
Form: 1 mg/ml in DI water.
Purity: Synthetic peptide p-OLIG2 (S147) . (Note: the amino acid sequence is proprietary). The purity is > 98%.
Storage temp: Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.
Alternative names: Oligodendrocyte transcription factor 2; Oligo2; Class B basic helix-loop-helix protein 1; bHLHb1; Class E basic helix-loop-helix protein 19; bHLHe19; Protein kinase C-binding protein 2; Protein kinase C-binding protein RACK17; OLIG2; BHLHB1; BHLHE19; PRKCBP2; RACK17
Additional info: This peptide can be used with studies using AP0734 p-OLIG2 (S147) pAb .

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