p21 Antibody

Cat no: 252156

Supplier: ABBIOTEC

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Description
Additional Information

Cyclin-dependent kinase inhibitor 1 (p21) is an important intermediate by which p53/TP53 mediates its role as an inhibitor of cellular proliferation in response to DNA damage. P21 binds to and inhibits cyclin-dependent kinase activity,Porcinereventing phosphorylation of critical cyclin-dependent kinase substrates and blocking cell cycle progression. p21 functions in the nuclear localization and assembly of the cyclin D-CDK4 comple, Xenopus/Amphibian, and promotes its kinase activity towards RB1. At higher stoichiometric ratios,Porcine21 inhibits the kinase activity of the cyclin D-CDK4 comple, Xenopus/Amphibian,.

Catalogue number:	252156
Reactivities:	Human
Applications:	Immunohistochemistry
Size:	0.1 mg
Accession:	P38936
Antigen:	KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human p21.
Format:	Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4, 1% BSA with 0.09% sodium azide. Antibody was purified by immunogen affinity chromatography.
P type:	Rabbit Polyclonal Antibody
Isotype:	Rabbit Ig
Additional info:	P21; CDKN1A; CAP20; CDKN1; CIP1; MDA6; PIC1; SDI1; WAF1; Cyclin-dependent kinase inhibitor 1;CDK-interacting protein 1; Melanoma differentiation-associated protein 6; MDA-6