p27 Antibody

Cat no: 251260

Supplier: ABBIOTEC

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Description
Additional Information

Cyclin-dependent kinase inhibitor p27 (p27) is a regulator of cell cycle progression. p27 is involved in G1 arrest. P27 is a potent inhibitor of cyclin E- and cyclin A-CDK2 comple, Xenopus/Amphibian,es. P27 forms a comple, Xenopus/Amphibian, with cyclin type D-CDK4 comple, Xenopus/Amphibian,es and is involved in the assembly, stability, and modulation of CCND1-CDK4 comple, Xenopus/Amphibian, activation. P27 acts either as an inhibitor or an activator of cyclin type D-CDK4 comple, Xenopus/Amphibian,es depending on its phosphorylation state and/or stoichometry. Defects in CDKN1B are the cause of multiple endocrine neoplasia type 4 (MEN4). Multiple endocrine neoplasia (MEN) syndromes are inherited cancer syndromes of the thyroid. MEN4 is a MEN-like syndrome with a phenotypic overlap of both MEN1 and MEN2.

Catalogue number:	251260
Reactivities:	Human, Mouse, Chicken/Bird, Rabbit
Applications:	Immunohistochemistry
Size:	0.1 mg
Accession:	P46527
Antigen:	KLH-conjugated synthetic peptide encompassing a sequence within the center region of human p27.
Format:	Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.
P type:	Rabbit Polyclonal Antibody
Isotype:	Rabbit Ig
Additional info:	p27; Kip1; p27/kip1; Cyclin-dependent kinase inhibitor 1B; Cyclin-dependent kinase inhibitor p27; p27Kip1; CDKN1B; KIP1