P2RX4 (P2X Purinoceptor 4, P2X4, ATP Receptor, Purinergic Receptor)

Cat no: P1003-09

Supplier: United States Biological

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Receptor for ATP that acts as a ligand-gated ion channel. This receptor is insensitive to the antagonists PPADS and suramin. Applications: Suitable for use in ELISA and Western Blot. Other applications not tested. Recommended Dilution: ELISA: 1:32,000 Western Blot: 0.3-1ug/ml, observed in human kidney lysates on ~60kD bands Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Catalogue number:	P1003-09
Reactivities:	Human, Mouse, Rat, Bovine, Canine
Hosts:	Goat
Applications:	ELISA, Western Blot
Size:	100ug
Form:	Supplied as a liquid in Tris saline, 0.02% sodium azide, pH 7.3, 0.5% BSA.
P type:	Pab
Purity:	Purified by immunoaffinity chromatography.
References:	1. Yuan H, Zhu X, Zhou S, Chen Q, Zhu X, Ma X, He X, Tian M, Shi X. Role of mast cell activation in inducing microglial cells to release neurotrophin. J Neurosci Res. 2010 May 1;88(6):1348-54. 2. Freeman KW, Bowman BR, Zetter BR. Regenerative protein thymosin beta-4 is a novel regulator of purinergic signaling. FASEB J. 2011 Mar;25(3):907-15.
Additional info:	Recognizes human P2RX4. Species Crossreactivity: Mouse. Species sequence homology: Bovine, canine and rat.

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P2RX4 (P2X Purinoceptor 4, P2X4, ATP Receptor, Purinergic Receptor)

Cat no: P1003-09

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