The CD p53 autoantibodies ELISA shows a high signal to noise ratio. Rohayem et al. evaluated the potential of three commercial p53 autoantibodies ELISAs to provide correct diagnostic classification by use of ROC curve analysis using sera of 72 patients with suspicion of malignancy and sera of 72 healthy blood donors as control. Among the three tests used, the solid-phase ELISA (CD) showed the highest diagnostic accuracy (AUC = 0.902) with a significant difference from other tests. CD offers an assay, which enables easy quantitative determination of p53 autoantibodies. Therefore you are able to monitor patient specific levels of p53 antibodies during the course of the disease or during therapeutic manipulations.