p57/KIP2 Antibody

Cat no: 251189

Supplier: ABBIOTEC

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Description
Additional Information

p57/KIP2 is a potent tight-binding inhibitor of several G1 cyclin/CDK comple, Xenopus/Amphibian,es (cyclin E-CDK2, cyclin D2-CDK4, and cyclin A-CDK2) and, to a lesser e, Xenopus/Amphibian,tent, of the mitotic cyclin B-CDC2. p57/KIP2 is a negative regulator of cell proliferation and plays a role in the maintenance of the non-proliferative state throughout life. Defects in CDKN1C are a cause of Beckwith-Wiedemann syndrome (BWS). BWS is a genetically heterogeneous disorder characterized by anterior abdominal wall defects including e, Xenopus/Amphibian,omphalos (omphalocele),Porcinere- and postnatal overgrowth, and macroglossia.

Catalogue number:	251189
Reactivities:	Human, Mouse, Bovine, Rabbit
Applications:	Immunohistochemistry
Size:	0.1 mg
Accession:	P49918
Antigen:	KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human p57/KIP2 A.
Format:	Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.
P type:	Rabbit Polyclonal Antibody
Isotype:	Rabbit Ig
Additional info:	Cdkn1c; p57/Kip2; p57; KIP2; Cyclin-dependent kinase inhibitor 1C; Cyclin-dependent kinase inhibitor p57; p57KIP2