P63 Antibody

Cat no: 250524

Supplier: ABBIOTEC

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Description
Additional Information

Tumor protein 63 (p63) acts as a sequence specific DNA binding transcriptional activator or repressor. The isoforms contain a varying set of transactivation and auto-regulating transactivation inhibiting domains thus showing an isoform specific activity. p63 in conjunction with p73 initiates p53 dependent apoptosis in response to environmental stimuli such as DNA damage and hypo, Xenopus/Amphibian,ia. p63 is also involved in Notch signaling and regulation of epithelial morphogenesis. Defects in p63 are the cause of multiple ectodermal dysplasia syndromes, a group of developmental disorders affecting tissues of ectodermal origin.

Catalogue number:	250524
Reactivities:	Human, Mouse, Rabbit
Applications:	Immunohistochemistry
Size:	0.1 mg
Accession:	Q9H3D4
Antigen:	KLH-conjugated synthetic peptide encompassing a sequence within the center region of human p63.
Format:	Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.
P type:	Rabbit Polyclonal Antibody
Isotype:	Rabbit Ig
Additional info:	Tumor protein 63; p63; Transformation-related protein 63; TP63; Tumor protein p73-like; p73L; p51; p40; Keratinocyte transcription factor KET; Chronic ulcerative stomatitis protein; CUSP; P73H; TP73L