p70-S6K Antibody

Cat no: 251131

Supplier: ABBIOTEC

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Description
Additional Information

70 kDa ribosomal protein S6 kinase 1 (p70-S6K) acts to integrate nutrient and growth factor signals in regulation of protein synthesis, cell proliferation, cell growth, cell cycle progression and cell survival. P70-S6K is a downstream effector of the mTOR signaling pathway. P70-S6K phosphorylates specifically ribosomal protein S6 in response to insulin or several classes of mitogens. During translation initiation, the inactive form associatess with the eIF-3 comple, Xenopus/Amphibian, under conditions of nutrient depletion. Mitogenic stimulation leads to phosphorylation and dissociation from the eIF-3 comple, Xenopus/Amphibian, and the free activated form can phosphorylate other translational targets including EIF4B.

Catalogue number:	251131
Reactivities:	Human, Mouse, Rabbit
Size:	0.1 mg
Accession:	P23443
Antigen:	KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human p70-S6K.
Format:	Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was immunoaffinity purified with c-terminal p70-S6K on agarose.
P type:	Rabbit Polyclonal Antibody
Isotype:	Rabbit Ig
Additional info:	Ribosomal protein S6 kinase beta-1; Ribosomal protein S6 kinase I; S6K1; S6K; 70 kDa ribosomal protein S6 kinase1; p70 S6 kinase alpha; p70(S6K)-alpha; p70-S6K; P70S6K; p70-alpha; RPS6KB1