PAFAH, Recombinant, Human (Platelet-activating Factor Acetylhydrolase, PAF Acetylhydrolase, 1-alkyl-2-acetylglycerophosphocholine Esterase, 2-acetyl-1-alkylglycerophosphocholine Esterase, Group-VIIA Phospholipase A2, gVIIA-PLA2, LDL-associated Phospholipa

LP-PLA2 is an enzyme produced by inflammatory cells and hydrolyzes oxidised phospholipids in low-density lipoprotein (LDL). In the blood, it travels mainly with LDL and less than 20% is associated with high-density lipoprotein. LP-PLA2 is involved in the development of atherosclerosis and is a marker for cardiac disease.\n\nSource: \nRecombinant corresponding to aa22-441 from mature human LP-PLA2, fused to 6x His-tag at N-terminal, expressed in E. coli.\n\nStorage and Stability:\nMay be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

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SPECIFICATIONS

Catalog Number

P4257-84N

Size

10ug

Form

Supplied as liquid.

Purity

~95% (SDS-PAGE)

References

1. Zalewski A. et al (2005) Arteriosclerosis, Thrombosis, and Vascular Biology 25: 923. 2. Mohler E.R. et al (2008) Journal of American College of Cardiology 51: 1632-1641.