PAK-1/2/3 (Thr402) Antibody

Cat no: 252569

Supplier: ABBIOTEC

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Description
Additional Information

Serine/threonine-protein kinase PAK-1 (PAK-1) is a protein kinase that acts on a variety of targets. PAK-1 is the GTPase effector that links the Rho-related GTPases to the JNK MAP kinase pathway. PAK-1 is activated by CDC42 and RAC1, and is involved in dissolution of stress fibers and reorganization of focal comple, Xenopus/Amphibian,es. PAK-1 is involved in regulation of microtubule biogenesis through phosphorylation of TBCB. PAK-1 activity is inhibited in cells undergoing apoptosis,Porcineotentially due to binding of CDC2L1 and CDC2L2. Autophosphorylation of Thr402 has been found to be essential for activation of PAK.

Catalogue number:	252569
Reactivities:	Mouse, Bovine, Rabbit
Applications:	Western Blot
Size:	0.1 ml
Accession:	P35465
Antigen:	KLH-conjugated synthetic phosphopeptide encompassing a sequence surrounding Thr402 of rat PAK-1, 2, 3.
Format:	Each vial contains 0.1 ml IgG in HEPES pH7.5, 150 mM NaCl, 0.01% BSA and 50% glycerol. Antibody was purified by immunogen affinity chromatography.
P type:	Rabbit Polyclonal Antibody,Porcinehosphospecific Antibody
Isotype:	Rabbit IgG
Additional info:	Serine/threonine-protein kinase PAK 1; p21-activated kinase 1; PAK-1; p65-PAK; Alpha-PAK; PAK1