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Paprotrain ((Z)-alpha-(3-Pyridinylmethylene)-1H-indole-3-acetonitrile)

Paprotrain ((Z)-alpha-(3-Pyridinylmethylene)-1H-indole-3-acetonitrile)

Cat no: 045127

Supplier: United States Biological
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Cell permeable kinesin-specific MKLP-2 (mitotic kinesin-like protein 2) inhibitor. Inhibits the recruitment of the chromosome passenger proteins survivin and aurora B to the central spindle during anaphase chromosome segregation. Storage and Stability: Short-term Storage: +4 degrees C Long-term Storage: -20 degrees C Stable for at least 2 years after receipt when stored at -20 degrees C.
Catalogue number: 045127
Size: 1mg
Purity: >98% (NMR)
Alternative names: (Z)-alpha-(3-Pyridinylmethylene)-1H-indole-3-acetonitrile
References: Product Reference: ?Relocation of Aurora B and Survivin from Centromeres to the Central Spindle Impaired by a Kinesin-Specific MKLP-2 Inhibitor: S. Tcherniuk, et al.; Angew. Chem. (Int'l Ed.) 49, 8228 (2010) ?

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