Parathyroid Hormone, Recombinant, Human (PTH, PTH1, Parathormone, Parathyrin)

Supplier:

United States Biological

Cat no: P3109-28F

Parathyroid Hormone, Recombinant, Human (PTH, PTH1, Parathormone, Parathyrin)

Source:\nRecombinant corresponding to 34aa of human Parathyroid Hormone expressed in E.coli is a single, non-glycosylated, polypeptide chain.\n\nMolecular Weight:\n~4.1kD\n\nBiological Activity:\nThe activity calculated by UMR106 cell/cAMP method corresponding to a specific activity of 1.0x104 Units/mg.\n\nDimers and Aggregates:\n(same/less than)1% (SDS-PAGE)\n\nProtein Content\nProtein quantitation was carried out by two independent methods:1. UV spectroscopy at 280nm. 2. Analysis by RP-HPLC, using a calibrated solution of PTH as a Reference Standard.\n\nStorage and Stability:\nLyophilized powder may be stored at -20 degrees C. Stable for 12 months at -20 degrees C. Reconstitute with sterile ddH2O, HSA or BSA. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

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SPECIFICATIONS

Catalog Number

P3109-28F

Size

100ug

Form

Supplied as a lyophilized powder. No preservative added. Reconstitute with sterile dH2O, 0.1% HSA or BSA to (same/more than)0.1mg/ml.

Purity

~98% (RP-HPLC, Anion-exchange FPLC, SDS-PAGE) Endotoxin: (same/less than)0.1ng/ug (IEU/ug)

References

1. Canine hyperadrenocorticism: effects of trilostane on parathyroid hormone, calcium and phosphate concentrations. J Small Anim Pract 2005 Nov;46(11):537-42. 2. Relationship between serum parathyroid hormone levels, vitamin D sufficiency, and calcium intake. JAMA 2005 Nov 9;294(18):2336-41. 3. Intraoperative parathyroid hormone testing improves cure rates in patients undergoing minimally invasive parathyroidectomy. Surgery 2005 Oct;138(4):583-7; discussion 587-90. 4. [Parathyroid hormone for osteroporsis: why and who to treat?]. Rev Med Suisse 2005 Oct 5;1(35):2272-4 , 2276-7. 5. Parathyroid hormone and biochemical profile in chronic kidney disease patients in South India. Hemodial Int 2005 Jan;9(1):63-7. 6. Relationship between parathyroid calcium-sensing receptor expression and potency of the calcimimetic, cinacalcet, in suppressing parathyroid hormone secretion in an in vivo murine model of primary hyperparathyroidism. Eur J Endocrinol 2005 Oct;153(4):587-94.

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SUPPLIER INFO

United States Biological

Address:

4 Technology Way, Salem, MA 01970, US

Phone:

+1 800 520 3011

Website:

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