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PBK (I4) Peptide

PBK (I4) Peptide

Cat no: BS1571P

Supplier: Bioworld Technology, Inc.
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PBK (PDZ binding kinase) belongs to the serine/threonine protein kinase family. It is related to the dual specific mitogen-activated protein kinase kinase (MAPKK) family and phosphorylates MAP kinase p38. It is active only in mitosis. When phosphorylated it forms a complex with TP53, leading to TP53 destabilization and attenuation of G2/M checkpoint during doxorubicin-induced DNA damage. It makes a kinase-substrate complex with cdk1/cyclin B1 and PRC1 on microtubules during mitosis, enhances the cdk1/cyclin B1-dependent phosphorylation of PRC1 and thereby strongly promotes cytokinesis. It may play a role in the activation of lymphoid cells.
Catalogue number: BS1571P
Applications: Block/Neutralize/Inhibit
Swiss prot: Q96KB5
Form: 1 mg/ml in DI water.
Purity: Synthetic peptide PBK (I4). (Note: the amino acid sequence is proprietary). The purity is > 98%.
Storage temp: Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.
Alternative names: SPK; TOPK; Nori-3; FLJ14385
Additional info: This peptide can be used with studies using BS1571 PBK (I4) pAb.

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