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PCI-34051

PCI-34051

Cat no: 019152

Supplier: United States Biological
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PCI-34051 is a potent, histone deacetylase 8 (HDAC8)-specific inhibitor. PCI-34051 induces caspase-dependent apoptosis in cell lines derived from T-cell lymphomas or leukemias. PCI-34051 did not affect other hematopoietic or solid tumor lines. PCI-34051 treatment has been shown to significantly reduce cholesterol accumulation in Niemann-Pick type C1 gene mutated human fibroblast.
Catalogue number: 019152
Size: 10mg
Alternative names: N-hydroxy-1-(4-methoxybenzyl)-1H-indole-6-carboxamide; PCI 34051;
References: Balasubramanian, S. et al.: Leukemia, 22, 1026 (2008); Pipalia, N.H. et al.: Proc. Nat. Acad. Sci. USA, 108, 5620 (2011);

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