PCNA (Proliferating Cell Nuclear Antigen) Kit, BioAssay(TM)

Supplier:

United States Biological

Cat no: P3115-11G

PCNA (Proliferating Cell Nuclear Antigen) Kit, BioAssay(TM)

PCNA (Proliferating Cell Nuclear Antigen) was previously known as cyclin. PCNA is a nonhistone protein (MW 36kD) found in the nucleus that plays a role in the initiation of cell proliferation by mediating DNA polymerase. PCNA levels are elevated in the S, G2, and M phases of cell mitosis in normal and malignant tissues. PCNA expression has a broad correlation with mitotic activity and can be used as a marker for cell proliferation. PCNA has proven useful for proliferative studies of normal and neoplastic tissues both in vivo and in vitro. (1

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SPECIFICATIONS

Catalog Number

P3115-11G

Size

1Kit

Applications

IHC

Reactivities

Hum, Mouse, Rat, NHP, Rabbit, Yeast/Fun

References

1. Waseem, N.H. and Lane, D.P., J. Cell Sci. 90: 121 (1990). 2. Deravn, P.A., et al., Am. J. Clin. Pathol. 97(Supp 1): S21-S28 (1992). 3. Bravo, R. and MacDonald-Bravo, H., J. Cell Biol. 105: 1549-1554 (1987). 4. Linden, M.D., et al., Am. J. Clin. Pathol. 97: 4-13 (1992). 5. van Dierendonek, J.H., et al., Am. J. Pathol. 138: 1165-1172 (1991). 6. Deckert, M., et al., Cancer Res. Clin. Oncol. 115: 179 (1989). 7. Robbins, et al., Arch. Pathol. Lab. Med. 111: 841-845 (1987).

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SUPPLIER INFO

United States Biological

Address:

4 Technology Way, Salem, MA 01970, US

Phone:

+1 800 520 3011

Website:

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