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Products PD 150,606 (3-(4-Iodophenyl)-2-mercapto-(Z)-2-propenoic acid)
| Catalogue number: | 045128 |
| Size: | 5mg |
| Purity: | >98% (NMR) |
| Alternative names: | 3-(4-Iodophenyl)-2-mercapto-(Z)-2-propenoic acid |
| References: | Product Reference: ?Modulation of hypoxia-induced calpain activity in rat renal proximal tubules: C.L. Edelstein, et al.; Kidney Int. 50, 1150 (1996) ?An alpha-mercaptoacrylic acid derivative is a selective nonpeptide cell-permeable calpain inhibitor and is neuroprotective: K.K. Wang, et al.; PNAS 93, 6687 (1996) ?Alpha-mercaptoacrylic acid derivatives as novel selective calpain inhibitors: K.K. Wang, et al.; Adv. Exp. Med. Biol. 389, 95 (1996) ?Crystal structure of calcium bound domain VI of calpain at 1.9A resolution and its role in enzyme assembly, regulation, and inhibitor binding: G.D. Lin, et al.; Nat. Struct. Biol. 4, 539 (1997) ?An alpha-mercaptoacrylic acid derivative (PD150606) inhibits selective motor neuron death via inhibition of kainate-induced Ca2+ influx and not via calpain inhibition: L. Van den Bosch, et al.; Neuropharmacology 42, 706 (2002) ?Calpain, an upstream regulator of thymocyte apoptosis: M.K. Squier & J.J. Cohen; J. Immunol. 158, 3690 (1997) ? |
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