PDGFRB Antibody

Cat no: 250817

Supplier: ABBIOTEC

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Description
Additional Information

The PDGF Receptor Type Bovine, a 190kD protein, appears to bind only the PDGF BB homodimer with high affinity, whereas the PDGF receptor type A (Alpha platelet-derived growth factor receptor precursor, CD140a antigen), a 170kD protein, binds all three isoforms of PDGF with high affinity. Both receptors are trans membranous, ligand activated protein tyrosine kinases which phosphorylate a number of important signal transduction proteins that are bound with differential affinities via SH2 domains.

Catalogue number:	250817
Reactivities:	Human, Mouse, Rabbit
Applications:	Immunohistochemistry
Size:	0.1 mg
Accession:	P09619
Antigen:	KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human PDGF-R-B.
Format:	Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.
P type:	Rabbit Polyclonal Antibody
Isotype:	Rabbit IgG
Additional info:	PDGF-R-B; Beta-type platelet-derived growth factor receptor; PDGF-R-beta; CD140 antigen-like family member B; CD140b; PDGFRB