PDLIM5 (S257) pAb

The protein encoded by the PDLIM5 (PDZ and LIM domain 5) gene is a LIM domain protein. LIM domains are cysteine rich double zinc fingers composed of 50-60 amino acids that are involved in protein-protein interactions. LIM domain containing proteins are scaffolds for the formation of multiprotein complexes. They are involved in cytoskeleton organization, where they interact with various PKC isoforms through the LIM domains and with actin and alpha actinin through the PDZ domain. In addition, they are involved in cell lineage specification, organ development, and oncogenesis. This protein is also a member of the Enigma class of proteins, a family of proteins that have a 100 amino acid PDZ domain in the N terminus and 1 to 3 LIM domains in the C terminus. Multiple transcript variants encoding different isoforms have been found for this gene, but not all of them have been fully characterized.

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SPECIFICATIONS

Catalog Number

BS3197

Size

100ug/100ul

Applications

WB

Hosts

Rabbit

Reactivities

Hum

Form

liquid

Purity

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Antigen

Synthetic peptide, corresponding to amino acids 223-270 of Human PDLIM5.

Species

PDLIM5 (S257) pAb detects endogenous levels of PDLIM5 protein.

Dilutions

WB: 1:500~1:1000

Swiss Prot

Q96HC4

Storage Temp

Store at 4 degrees C short term. Aliquot and store at -20 degrees C long term. Avoid freeze-thaw cycles.

Concentration

1ug/ul