Home  >  Products  >  PDX1 (Pancreas/Duodenum Homeobox Protein 1, Insulin Promoter Factor 1, Islet/Duodenum Homeobox-1, Somatostatin-transactivating Factor 1, Insulin Upstream Factor 1, Glucose-sensitive Factor, PDX-1, IPF-1, IDX-1, STF-1, IUF-1, GSF, IPF1)
PDX1 (Pancreas/Duodenum Homeobox Protein 1, Insulin Promoter Factor 1, Islet/Duodenum Homeobox-1, Somatostatin-transactivating Factor 1, Insulin Upstream Factor 1, Glucose-sensitive Factor, PDX-1, IPF-1, IDX-1, STF-1, IUF-1, GSF, IPF1)

PDX1 (Pancreas/Duodenum Homeobox Protein 1, Insulin Promoter Factor 1, Islet/Duodenum Homeobox-1, Somatostatin-transactivating Factor 1, Insulin Upstream Factor 1, Glucose-sensitive Factor, PDX-1, IPF-1, IDX-1, STF-1, IUF-1, GSF, IPF1)

Cat no: P3127-05T

Supplier: United States Biological
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PDX1 is a transcriptional activator of several genes, including insulin, somatostatin, glucokinase, islet amyloid polypeptide, and glucose transporter type 2. This nuclear protein is involved in the early development of the pancreas and plays a major role in glucose-dependent regulation of insulin gene expression. Defects in the gene encoding PDX1 are a cause of pancreatic agenesis, which can lead to early-onset insulin-dependent diabetes mellitus (NIDDM), as well as maturity onset diabetes of the young type 4 (MODY4). Applications: Suitable for use in ELISA. Other applications not tested. Recommended Dilution: ELISA: 1:1000 Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Catalogue number: P3127-05T
Reactivities: Human, Mouse, Rat, Canine
Hosts: Goat
Applications: ELISA
Size: 100ug
Form: Supplied as a liquid in Tris saline, 0.02% sodium azide, pH 7.3, 0.5% BSA.
P type: Pab
Purity: Purified by immunoaffinity chromatography.
References: 1. Wells JM, Melton DA. Vertebrate endoderm development. Annu Rev Cell Dev Biol. 1999;15:393-410. Review.
Additional info: Recognizes IPF1. Species sequence homology: Canine, human, mouse and rat.

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