PDZD11, Recombinant, Human, aa1-140, His-Tag (PDZ Domain-containing Protein 11, AIPP1, PDZK11, PISP)

Supplier:

United States Biological

Cat no: 138709

PDZD11, Recombinant, Human, aa1-140, His-Tag (PDZ Domain-containing Protein 11, AIPP1, PDZK11, PISP)

PDZD11, also known as AIPP1a, is a cytosolic protein which contains one PDZ (DHR) domain. This protein bears resemblance to members of the MALS / VELIS family of proteins. It contains but one PDZ domain that apparently interacts with the C-terminus of partner proteins. PDZD11 is ubiquitously expressed, and appears to target calcium and copper ATPases to basolateral cell membranes. It is a transiently interacting partner of the PMCA b-splice forms that may play a role in their sorting to or from the plasma membrane. \n\nSource:\nRecombinant protein corresponding to aa1-140 from human PDZD11 at N-terminal, fused to His-tag expressed in E.coli. \n\nMolecular Weight: \n~18.5kD (163aa)\n\nAA Sequence:\nMGSSHHHHHH SSGLVPRGSH MGS SQLGIFISKV IPDSDAHRAG LQEGDQVLAV NDVDFQDIEH SKAVEILKTA REISMRVRFF PYNYHRQKER TVH MDSRIPY DDYPVVFLPA YENPPAWIPP HERVHHPDYN NELTQFLPRT ITLKKPPGAQ LGFNIRGGKA\n\nStorage and Stability:\nMay be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

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SPECIFICATIONS

Catalog Number

138709

Size

50ug

Form

Supplied as a liquid in 20mM tris-HCl buffer, pH 8.0, 0.15M sodium chloride, 1mM DTT, 20% glycerol.

Purity

~90% (SDS-PAGE)

References

1. Stephenson SE., et al. (1996). J Biol Chem. 280(39):33270-9. 2. Goellner GM, et al. (2003). Ann N Y Acad Sci. 986:461-71.

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SUPPLIER INFO

United States Biological

Address:

4 Technology Way, Salem, MA 01970, US

Phone:

+1 800 520 3011

Website:

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