PE anti-human CD119 (IFN-gamma R alpha chain)

CDw119 is a 90-100 kD type I transmembrane protein, also known as IFN-gamma R alpha chain or IFN-gammaRI. The IFN-gamma receptor is a complex of a high affinity IFN-gamma-binding chain (aka, IFN-gamma R alpha chain) and a second accessory protein required for signal transduction known as IFN-gamma R beta chain. The IFN-gamma R alpha chain is a member of the class II cytokine receptor family. Binding of IFN-gamma induces receptor dimerization and internalization. Signal transduction involves Jak1 and Jak2 protein kinases and involves STAT1 activation. The IFN-gamma receptor is expressed at moderate levels on virtually every cell with the exception of erythrocytes.

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SPECIFICATIONS

Catalog Number

308704

Size

100 tests

Applications

FC

Hosts

Mouse

Reactivities

Hum

Clone

GIR-94

Antigen

Human IFN-gammaRalpha, purified from human placenta

Gene Id

3459

Isotype

Mouse IgG2b, kappa

Clonality

Monoclonal

Dilutions

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. Test size products are transitioning from 20 microl to 5 microl per test. Please check your vial or your CoA to find the suggested use of this reagent per million cells in 100 microl staining volume or per 100 microl of whole blood. It is recommended that the reagent be titrated for optimal performance for each application. Read more at www.biolegend.com/testsize regarding the test size change.

Storage Temp

4 C

Concentration

Shipping Temp

Ambient RT

Storage Buffer

The antibody solution should be stored undiluted at 4C and protected from prolonged exposure to light. Do not freeze.

Alternative Names

IFN-gammaR, IFN-gammaRalpha, IFN-alpha R1, CDw119

Regulatory Status

RUO