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PE anti-human CD195 (CCR5)

PE anti-human CD195 (CCR5)

Cat no: 321406

Supplier: BioLegend
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CD195, also known as CCR5, is a 45 kD G protein-coupled seven transmembrane CC-chemokine receptor. It binds to MIP-1alpha, MIP-1beta, and RANTES and is expressed on a subset of T cells and monocytes. CD195 mediates an intracellular signal thought to induce differentiation and proliferation. CCR5 has also been shown to act as a co-receptor for R5 HIV-1 cell entry; modification of CCR5 by sulfation contributes to the efficiency of HIV-1 entry. The T21/8 monoclonal antibody has high affinity to CCR5 N-terminal epitope (Met1-Lys22) and is useful for flow cytometric analysis, immunoprecipitation, immunofluorescence microscopy, and ELISA assay of CCR5 expression.
Catalogue number: 321406
Reactivities: Human
Hosts: Mouse
Applications: Flow Cytometry
Size: 100 tests
Clone: T21/8
Gene: 1234
Dilutions: Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. Test size products are transitioning from 20 microl to 5 microl per test. Please check your vial or your CoA to find the suggested use of this reagent per million cells in 100 microl staining volume or per 100 microl of whole blood. It is recommended that the reagent be titrated for optimal performance for each application. Read more at www.biolegend.com/testsize regarding the test size change.
Storage buffer: The antibody solution should be stored undiluted at 4C and protected from prolonged exposure to light. Do not freeze.
Antigen: RBL-CCR5 cells
Isotype: Mouse IgG1, kappa
Clonality: Monoclonal
Regulatory status: RUO
Shipping temp: Ambient RT
Storage temp: 4 C
Alternative names: CCR5, C-C chemokine receptor type 5, HIV-1 fusion co-receptor
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