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PE anti-human CD215 (IL-15Ralpha)

PE anti-human CD215 (IL-15Ralpha)

Cat no: 330207

Supplier: BioLegend
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IL-15 receptor alpha (IL-15Ralpha) is a cytokine receptor with the structural homology to IL-2Ralpha (CD25). Both alpha receptors contain a group of beta sandwich protein called sushi domains. Similar to IL-2Ralpha, IL-15Ralpha is able to form a heterotrimer with their beta chain (CD122) and common gamma chain (gammac, CD132). But unlike IL-2Ralpha subunit, IL-15Ralpha itself binds to IL-15 with equivalent high affinity compared with the heterotrimeric complex. IL-15Ralpha is expressed as soluble or transmembrane forms by variety cells, such as activated monocytes, dendritic cells, CD8+ memory T cells, NK or NKT cells. IL-15Ralpha by itself forms stable complexes with IL-15 on cell surface and presents IL-15 in trans to neighboring cells. IL-15, like IL-2, is a pleiotropic four-helix bundle cytokine and plays a key role in promoting T and B cell survival and proliferation, preferentially in memory CD8+ T cell proliferation, and NK/NKT cell development.
Catalogue number: 330207
Reactivities: Human
Hosts: Mouse
Applications: Flow Cytometry
Size: 25 tests
Clone: JM7A4
Gene: 3601
Dilutions: Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. Test size products are transitioning from 20 microl to 5 microl per test. Please check your vial or your CoA to find the suggested use of this reagent per million cells in 100 microl staining volume or per 100 microl of whole blood. It is recommended that the reagent be titrated for optimal performance for each application. Read more at www.biolegend.com/testsize regarding the test size change.
Storage buffer: The antibody solution should be stored undiluted at 4C and protected from prolonged exposure to light. Do not freeze.
Isotype: Mouse IgG2b, kappa
Clonality: Monoclonal
Regulatory status: RUO
Shipping temp: Ambient RT
Storage temp: 4 C
Alternative names: IL-15R a chain
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