PE anti-human FPR3 (FPRL2)

Cat no: 357703

Supplier: BioLegend

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Description
Additional Information

FPR3, also known as FPRL2, belongs to the formyl peptide receptor family which includes FPR1, FPR2, and FPR3. Monocytes express FPR1, 2, and 3; upon differentiation into macrophages, expression of these receptors is maintained. Two ligands, humanin and F2L have been identified. Humanin is expressed in the heart, skeletal muscle, kidney, and liver but is not expressed in the immune system. F2L is a heme-binding protein first identified in the spleen. Binding of FPRL2 and F2L induces Ca2+ mobilization and neutrophil chemotaxis. Low level of expression of FPRL2 has also been reported on NK cells.

Catalogue number:	357703
Reactivities:	Human
Hosts:	Mouse
Applications:	Flow Cytometry
Size:	25 tests
Clone:	K102B9
Gene:	2359
Dilutions:	Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For immunofluorescent staining, the suggested use of this reagent is 5 microl per million cells or 5 microl per 100 microl of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.
Storage buffer:	The antibody solution should be stored undiluted at 4C and protected from prolonged exposure to light. Do not freeze.
Antigen:	DNA vaccine containing full length FPRL2.
Isotype:	Mouse IgG2a, kappa
Clonality:	Monoclonal
Regulatory status:	RUO
Shipping temp:	Ambient RT
Storage temp:	4 C
Alternative names:	FMLPY, FPRH2, formyl peptide receptor like 2, FPR3, formyl peptide receptor 3