PE anti-human Galectin-9

Galectin-9 is a mammalian lectin with a molecular weight around 50 kD. It is a member of the beta-galactoside-binding family. With two conserved carbohydrate recognition domains (CRDs), galectin-9 binds small beta-galactosides as well as complex glycoconjugates. HAVCR2/TIM3 has been reported as one of its ligands. Galectin-9 may be retained intracellularly or transported to the cell surface where it can be cleaved to generate a soluble form. Galectin-9 is expressed by lymphocytes, dendritic cells, granulocytes, eosinophils, astrocytes, endothelial cells, fibroblasts, and thymus epithelial cells. It can be induced by cytokines in various cell types and is involved in cell aggregation, adhesion, chemotaxis, and apoptosis; galectin-9 induces regulatory T cells and suppresses Th1 and Th17 responses.

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SPECIFICATIONS

Catalog Number

348905

Size

25 tests

Applications

FC, ICC

Hosts

Mouse

Reactivities

Hum

Clone

9M1-3

Antigen

Recombinant peptide from C-terminus of Galectin-9

Gene Id

3965

Isotype

Mouse IgG1, kappa

Clonality

Monoclonal

Dilutions

Each lot of this antibody is quality control tested by intracellular immunofluorescent staining with flow cytometric analysis. Test size products are transitioning from 20 microl to 5 microl per test. Please check your vial or your CoA to find the suggested use of this reagent per million cells in 100 microl staining volume or per 100 microl of whole blood. It is recommended that the reagent be titrated for optimal performance for each application. Read more at www.biolegend.com/testsize regarding the test size change.

Storage Temp

4 C

Concentration

Shipping Temp

Ambient RT

Storage Buffer

The antibody solution should be stored undiluted at 4C and protected from prolonged exposure to light. Do not freeze.

Alternative Names

Lgals9, Gal-9, Ecalectin, Tumor antigen HOM-HD-21, Ecalectin

Regulatory Status

RUO