PE anti-human IL-28RA

The IL-28RA, also known as IFNLR1, CRF-2-12, and LICR2, is a 57kD single-pass type I membrane glycoprotein containing one fibronectin III domain. Widely expressed in many tissue types, IL-28RA and IL-10RB dimerize to form the class II cytokine receptor for IL-28A (IFNlambda2), IL-28B (IFNlambda1) and IL-29 (IFNlambda3), also known as the type III interferons. Like type I interferons, the type III interferons have been shown to activate the Jak-STAT and MAPK signalling pathways and exhibit antiviral activity.

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SPECIFICATIONS

Catalog Number

337804

Size

100 tests

Applications

FC

Hosts

Mouse

Reactivities

Hum

Clone

MHLICR2a

Gene Id

163702

Isotype

Mouse IgG2a, kappa

Clonality

Monoclonal

Dilutions

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. Test size products are transitioning from 20 microl to 5 microl per test. Please check your vial or your CoA to find the suggested use of this reagent per million cells in 100 microl staining volume or per 100 microl of whole blood. It is recommended that the reagent be titrated for optimal performance for each application. Read more at www.biolegend.com/testsize regarding the test size change.

Storage Temp

4 C

Concentration

Shipping Temp

Ambient RT

Storage Buffer

The antibody solution should be stored undiluted at 4C and protected from prolonged exposure to light. Do not freeze.

Alternative Names

IFNLR1, CRF-2-12, LICR2

Regulatory Status

RUO