Home  >  Products  >  PE anti-human LAMP5
PE anti-human LAMP5

PE anti-human LAMP5

Cat no: 355803

Supplier: BioLegend
Star_fadedStar_fadedStar_fadedStar_fadedStar_faded
0 reviews | Write a Review Pencil
Lysosome-associated membrane protein 5 (LAMP5), also known as BAD-LAMP, UNC-43, and C20orf103, is a new member of LAMP family. It is a transmembrane glycosylated protein localized in the ER-Golgi intermediate compartment (ERGIC). LAMP5 shares sequence and structural homology with the canonical LAMP1 (CD107a) and LAMP2 (CD107b) molecules, harbors an endosomal addressing signal within its cytoplasmic tail, and contains several conserved cysteine residues that allow for the formation of particular structural loops known as LAMP folds. In mice, LAMP5 is expressed in postnatal cortical neurons of particular layers, where it is enriched in defined zones along neuronal projections. Human LAMP5, like its murine homolog, is principally expressed in brain; it is also specifically found in primary CD303 (BDCA-2)-positive pDCs (plasmacytoid dendritic cells). It represents a novel marker of human primary and transformed pDCs.
Catalogue number: 355803
Reactivities: Human
Hosts: Mouse
Applications: Flow Cytometry, Immunocytochemistry
Size: 25 tests
Clone: 124-40B
Gene: 24141
Dilutions: Each lot of this antibody is quality control tested by intracellular immunofluorescent staining with flow cytometric analysis. For immunofluorescent staining, the suggested use of this reagent is 5 microl per million cells or 5 microl per 100 microl of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.
Storage buffer: The antibody solution should be stored undiluted at 4C and protected from prolonged exposure to light. Do not freeze.
Antigen: Cells expressing C20orf103.
Isotype: Mouse IgG1, kappa
Clonality: Monoclonal
Regulatory status: RUO
Shipping temp: Ambient RT
Storage temp: 4 C
Alternative names: UNC-43, BADLAMP, BAD-LAMP, C20orf103, LAMP-5
See Full Product Listings >
Button_on Button_off_biosave Button_off_biosave Button_off_biosave Button_off_biosave Button_off_biosave Button_off_biosave