PE anti-human LOX-1

Cat no: 358604

Supplier: BioLegend

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Description
Additional Information

Lectin-like oxidized LDL receptor 1 (LOX-1), also known as CLEC8A, is a 31 kD, single pass, type II, transmembrane protein, member of the C-type lectin superfamily. LOX-1 is a scavenger receptor involved in endocytosis, phagocytosis, and cytokine production. LOX-1 is expressed by endothelial cells, smooth muscle cells, platelets, fibroblasts, and macrophages, and is upregulated by inflammatory and oxidative stimuli. LOX-1 recognized numerous ligands including lipoproteins, apoptotic cells heat shock proteins, C-reactive protein, and oxidized LDL. LOX-1 is implicated in atherosclerosis and vascular inflammation.

Catalogue number:	358604
Reactivities:	Human
Hosts:	Mouse
Applications:	Flow Cytometry
Size:	100 tests
Clone:	15C4
Gene:	4973
Dilutions:	Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For immunofluorescent staining, the suggested use of this reagent is 5 microl per million cells or 5 microl per 100 microl of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.
Storage buffer:	The antibody solution should be stored undiluted at 4C and protected from prolonged exposure to light. Do not freeze.
Antigen:	LOX-1 ectodomain:Fc fusion protein
Isotype:	Mouse IgG2a, kappa
Clonality:	Monoclonal
Regulatory status:	RUO
Shipping temp:	Ambient RT
Storage temp:	4 C
Alternative names:	OLR1, LOX1, LOXIN, SLOX1, CLEC8A, SCARE1