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PE anti-human Tim-4

PE anti-human Tim-4

Cat no: 354003

Supplier: BioLegend
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The T cell immunoglobulin and mucin domain containing protein (TIM) family encodes cell surface receptors that are involved in the regulation of T helper (Th-1 and Th-2) cell-mediated immunity. Tim-4, which is preferentially expressed on macrophages and dendritic cells, is the natural ligand of Tim-1. This binding leads to T-cell expansion and cytokine production. Unlike other members of the TIM family, TIM-4 lacks a putative tyrosine phosphorylation signal sequence in its intracellular domain. The TIM-4 gene maps to a locus associated with predisposition to asthma in both mice and humans and is connected to TIM-1-triggered Th2 responsiveness.
Catalogue number: 354003
Reactivities: Human
Hosts: Mouse
Applications: Flow Cytometry
Size: 25 tests
Clone: 9F4
Gene: 91937
Dilutions: Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For immunofluorescent staining, the suggested use of this reagent is 5 microl per million cells or 5 microl per 100 microl of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.
Storage buffer: The antibody solution should be stored undiluted at 4C and protected from prolonged exposure to light. Do not freeze.
Antigen: Human TIM-4- IgV Fc, fusion protein
Isotype: Mouse IgG1, kappa
Clonality: Monoclonal
Regulatory status: RUO
Shipping temp: Ambient RT
Storage temp: 4 C
Alternative names: SMUCKLER (Spleen, mucin-containg, knock-out of lymphotoxin (LT)), TIMD4, T-cell immunoglobulin and mucin domain containing 4
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