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PE anti-mouse CD120a (TNF R Type I/p55)

PE anti-mouse CD120a (TNF R Type I/p55)

Cat no: 113004

Supplier: BioLegend
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CD120a is a 55 kD Type I transmembrane protein, also known as Tumor Necrosis Factor Receptor Type I (TNFRI) or p55. It is expressed on a variety of cells at low levels. Resting T cells and erythrocytes express very little to no CD120a. This receptor binds both TNF-alpha and LT-alpha (also known as TNF-beta). In association with TRADD and RIP, the receptor crosslinking induced by TNF-alpha or LT-alpha trimers is critical for signal transduction, leading to apoptosis, NF-kB activation, increased expression of proinflammatory genes, tumor necrosis, and cell differentiation depending on cell type and differentiation state.
Catalogue number: 113004
Reactivities: Mouse
Hosts: Hamster
Applications: Flow Cytometry
Size: 200 microg
Clone: 55R-286
Gene: 21937
Dilutions: Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For immunofluorescent staining, the suggested use of this reagent is ? 1.0 microg per 106 cells in 100 microl volume. It is recommended that the reagent be titrated for optimal performance for each application.
Storage buffer: The antibody solution should be stored undiluted at 4C and protected from prolonged exposure to light. Do not freeze.
Concentration: 0.2 mg/ml
Antigen: E. coli-expressed extracellular domain of the mouse TNFRI protein
Isotype: Armenian Hamster IgG
Clonality: Monoclonal
Regulatory status: RUO
Shipping temp: Ambient RT
Storage temp: 4 C
Alternative names: TNFR type I, TNFRI, TNFR60, p55, TNFRSF1A
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