PE anti-mouse DcTRAIL-R1

Mouse Decoy Tumor Necrosis Factor-Related Apoptosis-Inducing Ligand (TRAIL) Receptor 1 (mDcTRAIL R1) is a GPI-anchored mouse TNF receptor super-family member that lacks a cytoplasmic death domain. It expresses on many cell types, including some tumor cells. mDcTRAIL R1 appears to have a negative effect against TRAIL receptors because it lacks an intracellular death domain, and produces a competitive blockage of TRAIL-mediated apoptosis. The role of the DcR1 in apoptosis has not yet been clarified.

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SPECIFICATIONS

Catalog Number

133804

Size

100 microg

Applications

FC

Reactivities

Mouse

Clone

mDcR1-3

Antigen

mDcTRAIL-R1-Fc

Gene Id

79201

Isotype

Armenian Hamster IgG

Clonality

Monoclonal

Dilutions

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For immunofluorescent staining, the suggested use of this reagent is ?0.25 microg per million cells in 100 microl volume. It is recommended that the reagent be titrated for optimal performance for each application.

Storage Temp

4 C

Concentration

0.2 mg/ml

Shipping Temp

Ambient RT

Storage Buffer

The antibody solution should be stored undiluted at 4C and protected from prolonged exposure to light. Do not freeze.

Alternative Names

TNFRH1, mSOB, Tumor necrosis factor receptor superfamily member 23, Tnfrsf23, Tumor necrosis factor receptor p60 homolog 1, TNF receptor family member SOB, Decoy TRAIL receptor 1, TNF receptor homolog 1

Regulatory Status

RUO