PE anti-mouse TCR Vbeta12

Cat no: 139703

Supplier: BioLegend

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Description
Additional Information

T cell receptor Vbeta12 (TCR Vbeta12) is a variant of TCR beta chain and, along with TCR alpha chain, forms the TCR heterodimer. In association with the CD3 complex, TCR alpha/beta is responsible for antigen recognition through interaction with MHC-peptide complex to initiate the T cell-mediated immune responses. The MR11-1 antibody reacts with the Vbeta12 TCR of mice bearing the b haplotype. It has been reported that Mtv-8 and Mtv-9 cause clonally deletion of Vbeta12+ T cells.

Catalogue number:	139703
Reactivities:	Mouse
Hosts:	Mouse
Applications:	Flow Cytometry
Size:	25 microg
Clone:	MR11-1
Gene:	21577
Dilutions:	Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For immunofluorescent staining, the suggested use of this reagent is ?0.06 microg per million cells in 100 microl volume. It is recommended that the reagent be titrated for optimal performance for each application.
Storage buffer:	The antibody solution should be stored undiluted at 4C and protected from prolonged exposure to light. Do not freeze.
Concentration:	0.2 mg/ml
Isotype:	Mouse IgG1, kappa
Clonality:	Monoclonal
Regulatory status:	RUO
Shipping temp:	Ambient RT
Storage temp:	4 C
Alternative names:	Vbeta12 T-cell receptor, T cell receptor beta 12